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PMID: 2452965 已发表 · ppublish 英语

Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid.

Medical hypotheses ·第 25 卷 ·第 4 期 ·1988-06-10

Eidinoff H

摘要

The author presents evidence from published papers of research done by numerous investigators that Multiple, Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid.

文献信息
期刊
Medical hypotheses
期刊简称
Med Hypotheses
发表日期
1988-06-10
收录日期
1988-06-10
更新日期
2013-11-21
语言
英语
国家/地区
United States
NLM ID
7505668
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