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PMID: 2456921 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila.

The EMBO journal ·Vol. 7 ·No. 4 ·1988-04-00 ·Pages 1087-96

Pongs O, Kecskemethy N, Müller R, Krah-Jentgens I, Baumann A, Kiltz HH, Canal I, Llamazares S, Ferrus A

Abstract

The Shaker locus of Drosophila contains a very large transcription unit. It is expressed predominantly in the nervous system by multiple, differential as well as alternative, splicing mechanisms into different, but functionally related proteins. The structure of the Shaker transcription unit and the properties of the encoded Shaker protein family provide a molecular basis for A channel diversity in excitable cells.

MeSH Terms

Amino Acid Sequence Animals Base Sequence Drosophila/genetics,metabolism Genes Ion Channels/metabolism Molecular Sequence Data Mutation Nervous System/metabolism Potassium/metabolism Transcription, Genetic

Chemicals

Ion Channels Potassium

Authors & Affiliations

9 authors, click to expand affiliations / ORCID

Pongs O

Ruhr-Universität Bochum, Lehrstuhl für Biochemie, FRG.

Kecskemethy N

Müller R

Krah-Jentgens I

Baumann A

Kiltz H H

Canal I

Llamazares S

Ferrus A

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30 references, click to expand

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Article Info

Journal

The EMBO journal

Abbr.

EMBO J

ISSN

0261-4189

Published

1988-04-00

Pages

1087-96

Language

English

Region

England

NLM ID

8208664

PMCID

PMC454441

Subset

Databases

GENBANK

X07131, X07132, X07133, X07134, Y00847

External Links

PubMed source PMC Full Text View journal details

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Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila.

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