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PMID: 2459130 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The association of prosomes with some of the intermediate filament networks of the animal cell.

The Journal of cell biology ·Vol. 107 ·No. 4 ·1988-10-00 ·Pages 1517-30

Grossi de Sa MF, Martins de Sa C, Harper F, Olink-Coux M, Huesca M, Scherrer K

Abstract

The small RNP complexes of defined morphology and biochemical composition termed prosomes, first isolated from the cytoplasm associated with repressed mRNA (Martins de Sa, C., M.-F. Grossi de Sa, O. Akhayat, F. Broders, and K. Scherrer. J. Mol. Biol. 1986. 187:47-493), were found also in the nucleus (Grossi de Sa, M.-F., C. Martins de Sa, F. Harper, O. Coux, O. Akhayat, P. Gounon, J. K. Pal, Y. Florentin, and K. Scherrer. 1988. J. Cell Sci. 89:151-165). Immunofluorescence, immunoelectron microscopy, and immunochemical studies using mAbs directed against some of the prosomal proteins of duck erythroblasts indicate that in the cytoplasm of HeLa and PtK cells, prosome antigens are associated with the intermediate filament network of the cytokeratin type.

MeSH Terms
Actin Cytoskeleton/ultrastructure Animals Blotting, Western Cell Line Cytoskeleton/ultrastructure Cytosol/metabolism Fluorescent Antibody Technique Humans Immunohistochemistry Intermediate Filaments/metabolism,ultrastructure Keratins Mice Microscopy, Electron Molecular Weight Ribonucleoproteins/metabolism Vimentin
Chemicals
Ribonucleoproteins Vimentin Keratins
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Grossi de Sa M F
Institut Jacques Monod, Paris, France.
Martins de Sa C
Harper F
Olink-Coux M
Huesca M
Scherrer K
References (31)
31 references, click to expand
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.107.4.1517
Published
1988-10-00
Pages
1517-30
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2115241
Subset
IM
Corrections
ErratumIn
-
External Links
PubMed source DOI: 10.1083/jcb.107.4.1517 PMC Full Text View journal details
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