Native interleukin 1 inhibitors.

Immunology today ·Vol. 10 ·No. 2 ·1989-02-00 ·Pages 61-6

Larrick JW

Abstract

Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1. In this review James Larrick discusses the biological and biochemical data available on several of these native interleukin 1 inhibitors, some of which have additional, unexpected activities.

MeSH Terms

Animals Cell Division/drug effects Feedback Gene Expression Regulation Humans Interleukin 1 Receptor Antagonist Protein Interleukin-1/antagonists & inhibitors,metabolism,physiology Macrophages/analysis Mice Mucoproteins/pharmacology Proteins/isolation & purification,pharmacology Receptors, Immunologic/metabolism Receptors, Interleukin-1 Sialoglycoproteins Signal Transduction Transforming Growth Factors/pharmacology Urine/analysis Uromodulin Virus Diseases/metabolism

Chemicals

IL1RN protein, human Il1rn protein, mouse Interleukin 1 Receptor Antagonist Protein Interleukin-1 Mucoproteins Proteins Receptors, Immunologic Receptors, Interleukin-1 Sialoglycoproteins UMOD protein, human Umod protein, mouse Uromodulin Transforming Growth Factors

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Larrick J W

Article Info

Journal

Immunology today

Abbr.

Immunol Today

ISSN

0167-5699

DOI

10.1016/0167-5699(89)90308-3

Published

1989-02-00

Pages

61-6

Language

English

Region

England

NLM ID

8008346

Subset

Corrections

CommentIn

PMID: 2803491

External Links

PubMed source DOI: 10.1016/0167-5699(89)90308-3

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Native interleukin 1 inhibitors.

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