Home LiteratureArticle Details
PMID: 2565864 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Physical mapping of DXS134 close to the DXS52 locus.

Human genetics ·Vol. 82 ·No. 1 ·1989-04-00 ·Pages 27-30

Bell MV, Patterson MN, Dorkins HR, Davies KE

Abstract

The locus DXS134 (cpX67) has been physically linked to the cluster of polymorphic loci DXS52, DXS15, and DXS33. A comparison of physical and genetic distance indicates a high rate of recombination in this region.

MeSH Terms
Genetic Linkage Haplotypes Humans Polymorphism, Genetic Polymorphism, Restriction Fragment Length Recombination, Genetic Restriction Mapping X Chromosome/ultrastructure
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Bell M V
Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford, UK.
Patterson M N
Dorkins H R
Davies K E
References (15)
15 references, click to expand
  1. The frequency of the fragile X chromosome among schoolchildren in Coventry.
    J Med Genet. 1986 Oct;23(5):396-9 PMID: 3783615
  2. The telomeric region of the human X chromosome long arm: presence of a highly polymorphic DNA marker and analysis of recombination frequency.
    Proc Natl Acad Sci U S A. 1985 May;82(9):2824-8 PMID: 2986139
  3. Resolution of DNA molecules greater than 5 megabases by contour-clamped homogeneous electric fields.
    Nucleic Acids Res. 1987 Oct 12;15(19):7865-76 PMID: 2959907
  4. Pulsed-field gel mapping studies in the vicinity of the fragile site at Xq27.3.
    Am J Med Genet. 1988 May-Jun;30(1-2):581-91 PMID: 3177471
  5. The fragile X syndrome in a large family. III. Investigations on linkage of flanking DNA markers with the fragile site Xq27.
    J Med Genet. 1987 Jul;24(7):413-21 PMID: 2886667
  6. Fragile X syndrome: a unique mutation in man.
    Annu Rev Genet. 1986;20:109-45 PMID: 3545058
  7. Separation of large DNA molecules by contour-clamped homogeneous electric fields.
    Science. 1986 Dec 19;234(4783):1582-5 PMID: 3538420
  8. Genetic mapping of the human X chromosome by using restriction fragment length polymorphisms.
    Proc Natl Acad Sci U S A. 1984 May;81(9):2836-9 PMID: 6326147
  9. Efficient isolation of X chromosome-specific single-copy probes from a cosmid library of a human X/hamster hybrid-cell line: mapping of new probes close to the locus for X-linked mental retardation.
    Am J Hum Genet. 1987 Apr;40(4):312-28 PMID: 2883888
  10. Close linkage of fragile X-mental retardation syndrome to haemophilia B and transmission through a normal male.
    Nature. 1983 Dec 15-21;306(5944):701-4 PMID: 6689201
  11. RFLP for linkage analysis of fragile X syndrome.
    Lancet. 1987 Jan 31;1(8527):280 PMID: 2880102
  12. Mapping of DNA markers close to the fragile site on the human X chromosome at Xq27.3.
    Nucleic Acids Res. 1987 Mar 25;15(6):2639-51 PMID: 2882476
  13. Molecular analysis of the Duchenne muscular dystrophy region using pulsed field gel electrophoresis.
    Cell. 1987 Jan 30;48(2):351-7 PMID: 3026644
  14. Report of the committee on the genetic constitution of the X and Y chromosomes.
    Cytogenet Cell Genet. 1987;46(1-4):277-315 PMID: 3507278
  15. Linkage heterogeneity and fragile X.
    Hum Genet. 1988 Apr;78(4):338-42 PMID: 2896154
Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00288266
Published
1989-04-00
Pages
27-30
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00288266 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2