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PMID: 2567430 Published · ppublish English Journal Article

Variable expression of P fimbriae in Escherichia coli urinary tract infection.

Lancet (London, England) ·Vol. 1 ·No. 8652 ·1989-06-24 ·Pages 1414-8

Lichodziejewska M, Topley N, Steadman R, Mackenzie RK, Jones KV, Williams JD

Abstract

Fresh urinary isolates were examined by immunofluorescence with polyclonal rabbit antibodies against type 1 and P fimbriae. This procedure showed P-fimbriate Escherichia coli in 22 of 24 samples from patients with asymptomatic bacteriuria, 24 of 26 samples from patients with cystitis, and 6 of 6 samples from patients with pyelonephritis. Type 1 fimbriae were expressed by less than 40% of isolates in all three groups. There was no relation between the presence of symptoms or the site of infection and fimbrial expression, of P or type 1, by bacteria adherent to freshly isolated uroepithelial cells.

MeSH Terms
Adolescent Adult Aged Aged, 80 and over Antibodies, Bacterial Bacterial Adhesion Blood Group Antigens/immunology Child Child, Preschool Escherichia coli/immunology,isolation & purification,metabolism Escherichia coli Infections/urine Fimbriae, Bacterial/analysis,classification,metabolism,ultrastructure Humans Methods Microscopy, Electron Middle Aged P Blood-Group System/immunology Urinary Tract Infections/urine
Chemicals
Antibodies, Bacterial Blood Group Antigens P Blood-Group System
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Lichodziejewska M
KRUF Institute of Renal Disease, University of Wales College of Medicine, Royal Infirmary, Cardiff.
Topley N
Steadman R
Mackenzie R K
Jones K V
Williams J D
Article Info
Journal
Lancet (London, England)
Abbr.
Lancet
ISSN
0140-6736
Published
1989-06-24
Pages
1414-8
Language
English
Region
England
NLM ID
2985213R
Subset
IM
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