Gastric glycerolipid as a receptor for Campylobacter pylori.

Lancet (London, England) ·Vol. 2 ·No. 8657 ·1989-07-29 ·Pages 238-41

Lingwood CA, Law H, Pellizzari A, Sherman P, Drumm B

Abstract

A species was detected in the lipid extract of human red blood cells and human and pig stomach tissue which was specifically recognised by isolates of Campylobacter pylori. The levels of this lipid were higher in human stomach antrum than in fundus and in adult compared with infant tissue samples. Chemical treatment of the purified substance suggests that it is a novel glycerolipid.

MeSH Terms

Animals Campylobacter/metabolism Chromatography, Ion Exchange Gastric Mucosa/microbiology Gastritis/microbiology Humans Receptors, Cell Surface Receptors, Immunologic/isolation & purification,metabolism Swine

Chemicals

Receptors, Cell Surface Receptors, Immunologic glycolipid receptor

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Lingwood C A

Department of Microbiology, Hospital for Sick Children, Toronto, Ontario, Canada.

Law H

Pellizzari A

Sherman P

Drumm B

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(89)90428-5

Published

1989-07-29

Pages

238-41

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/s0140-6736(89)90428-5 View journal details

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