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PMID: 2570755 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Relationship of Haemophilus influenzae type b pilus structure and adherence to human erythrocytes.

Infection and immunity ·Vol. 57 ·No. 10 ·1989-10-00 ·Pages 3259-60

Gilsdorf JR, Judd WJ, Cinat M

Abstract

Six strains of Haemophilus influenzae type b, some expressing immunologically different pili, showed identical patterns of binding to erythrocytes that were characterized for 38 blood group antigens. All six strains appeared to bind to the Anton antigen, as they agglutinated all erythrocytes tested except cord erythrocytes and those characterized as Lu(a-b-), dominant type, including Anton-negative cells.

MeSH Terms
Bacterial Adhesion Bacterial Proteins/metabolism,physiology Erythrocytes/metabolism,microbiology Fimbriae, Bacterial/metabolism,physiology Haemophilus influenzae/metabolism,physiology Humans Lutheran Blood-Group System/metabolism Structure-Activity Relationship
Chemicals
Bacterial Proteins Lutheran Blood-Group System
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gilsdorf J R
Department of Pediatrics and Communicable Diseases, C. S. Mott Children's Hospital, Ann Arbor, Michigan 48109-0244.
Judd W J
Cinat M
References (12)
12 references, click to expand
  1. Adherence of Haemophilus influenzae to human buccal and pharyngeal epithelial cells: relationship to pilation.
    J Med Microbiol. 1984 Aug;18(1):107-16 PMID: 6146722
  2. Observations on the Anton antigen and antibody.
    Vox Sang. 1982;43(4):220-2 PMID: 6182694
  3. Do pili play a role in pathogenicity of Haemophilus influenzae type B?
    Lancet. 1982 Oct 30;2(8305):960-2 PMID: 6127463
  4. Adherence of piliated Haemophilus influenzae type b to human oropharyngeal cells.
    J Infect Dis. 1982 Oct;146(4):564 PMID: 6126509
  5. Isolation and characterization of the alpha-sialyl-beta-2,3-galactosyl-specific adhesin from fimbriated Escherichia coli.
    Proc Natl Acad Sci U S A. 1987 May;84(10):3462-6 PMID: 2883653
  6. The erythrocyte and epithelial cell receptors for Haemophilus influenzae are expressed independently.
    Infect Immun. 1987 Oct;55(10):2355-8 PMID: 2888731
  7. Identification and characterization of E. coli type-1 pilus tip adhesion protein.
    Nature. 1988 Mar 17;332(6161):265-8 PMID: 2894612
  8. Structural and serological relatedness of Haemophilus influenzae type b pili.
    Infect Immun. 1988 May;56(5):1051-6 PMID: 2895739
  9. Interaction of Haemophilus influenzae with human erythrocytes and oropharyngeal epithelial cells is mediated by a common fimbrial epitope.
    Infect Immun. 1988 Jul;56(7):1800-6 PMID: 2454892
  10. Design and development of pilus vaccines for Haemophilus influenzae diseases.
    Pediatr Infect Dis J. 1989 Jan;8(1 Suppl):S54-61 PMID: 2564658
  11. Characterization of Haemophilus influenzae type b fimbriae.
    Infect Immun. 1984 Dec;46(3):787-96 PMID: 6150012
  12. Localization of the receptor-binding protein adhesin at the tip of the bacterial pilus.
    Nature. 1987 Jul 2-8;328(6125):84-7 PMID: 2885755
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1989-10-00
Pages
3259-60
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC260804
Subset
IM
Grants
NIAID NIH HHS · AI20934 · United States
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