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PMID: 2579059 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Escherichia coli 6S RNA is not essential for growth or protein secretion.

Journal of bacteriology ·Vol. 161 ·No. 3 ·1985-03-00 ·Pages 1156-61

Lee CA, Fournier MJ, Beckwith J

Abstract

The function of the stable 6S RNA of Escherichia coli is not known. Recently, it was proposed that the 6S RNA is a component of a bacterial signal recognition particle required for protein secretion. To test this proposal, we isolated a mutant that lacks the 6S RNA. Studies of the mutant show that the 6S RNA is not essential for growth or for protein secretion. The gene for the 6S RNA (ssr) maps near serA at 63 min on the E. coli genetic map.

MeSH Terms
Bacterial Proteins/metabolism Escherichia coli/genetics,growth & development Genes, Bacterial Mutation Peptides/metabolism Protein Sorting Signals RNA, Bacterial/genetics
Chemicals
Bacterial Proteins Peptides Protein Sorting Signals RNA, Bacterial
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lee C A
Fournier M J
Beckwith J
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31 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.161.3.1156-1161.1985
Published
1985-03-00
Pages
1156-61
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC215020
Subset
IM
Grants
NIGMS NIH HHS · GM 19351 · United States
External Links
PubMed source DOI: 10.1128/jb.161.3.1156-1161.1985 PMC Full Text View journal details
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