Home LiteratureArticle Details

PMID: 2645524 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria.

Nature ·Vol. 337 ·No. 6208 ·1989-02-16 ·Pages 620-5

Cheng MY, Hartl FU, Martin J, Pollock RA, Kalousek F, Neupert W, Hallberg EM, Hallberg RL, Horwich AL

Abstract

A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. hsp60 is a member of the 'chaperonin' class of protein factors, which include the Escherichia coli groEL protein and the Rubisco subunit-binding protein of chloroplasts.

MeSH Terms

Fungal Proteins/genetics Genes Genes, Fungal Heat-Shock Proteins/genetics,physiology Mitochondria/metabolism Mutation Plasmids Protein Processing, Post-Translational Saccharomyces cerevisiae/genetics,metabolism

Chemicals

Fungal Proteins Heat-Shock Proteins

Authors & Affiliations

9 authors, click to expand affiliations / ORCID

Cheng M Y

Yale University School of Medicine, Department of Human Genetics, New Haven, Connecticut 06510.

Hartl F U

Martin J

Pollock R A

Kalousek F

Neupert W

Hallberg E M

Hallberg R L

Horwich A L

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/337620a0

Published

1989-02-16

Pages

620-5

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/337620a0 View journal details

Analysis Services

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria.

Contact

WeChat Official Account