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PMID: 2647636 Published · ppublish English Journal Article

Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7.

Infection and immunity ·Vol. 57 ·No. 4 ·1989-04-00 ·Pages 1339-42

Francis DH, Moxley RA, Andraos CY

Abstract

Gnotobiotic piglets inoculated with Escherichia coli serotype O157:H7 strains that produced Shiga-like toxin II developed brain lesions similar to those observed in edema disease of swine, including arteriolar necrosis and malacia. Loss of ability to produce Shiga-like toxin II resulted in loss of ability to cause brain lesions.

MeSH Terms
Animals Brain Edema/microbiology,pathology,veterinary Edema Disease of Swine/microbiology,pathology Escherichia coli/classification,pathogenicity Escherichia coli Infections/microbiology,pathology,veterinary Germ-Free Life Swine Virulence
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Francis D H
Department of Veterinary Science, South Dakota State University, Brookings 57007-1396.
Moxley R A
Andraos C Y
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22 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.57.4.1339-1342.1989
Published
1989-04-00
Pages
1339-42
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC313274
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.57.4.1339-1342.1989 PMC Full Text View journal details
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