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PMID: 266187 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Secondary structural complementarity between DNA and proteins.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 74 ·No. 4 ·1977-04-00 ·Pages 1458-62

Church GM, Sussman JL, Kim SH

Abstract

A model for the complex between double-stranded DNA and a beta-ribbon (a two-stranded antiparallel beta-sheet) of proteins is proposed as one of the possible modes of structural recognition between DNA and proteins. In this model, the contact occurs on the narrow groove of DNA, and the symmetry elements as well as the repeat distances of DNA and the beta-ribbon coincide, thus providing favorable complementary contacts.

MeSH Terms

Binding Sites DNA Hydrogen Bonding Models, Molecular Nucleic Acid Conformation Protein Binding Protein Conformation Proteins

Chemicals

Proteins DNA

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Church G M

Sussman J L

Kim S H

References (14)

14 references, click to expand

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J Mol Biol. 1972 Jul 14;68(1):21-34 PMID: 4115109
Stereochemistry of actinomycin binding to DNA. I. Refinement and further structural details of the actinomycin-deoxyguanosine crystalline complex.
J Mol Biol. 1972 Jul 14;68(1):1-20 PMID: 4115108
Altered sequences changing the operator-binding properties of the Lac repressor: colinearity of the repressor protein with the i-gene map.
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3624-8 PMID: 4566452
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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.74.4.1458

Published

1977-04-00

Pages

1458-62

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC430798

Subset

External Links

PubMed source DOI: 10.1073/pnas.74.4.1458 PMC Full Text View journal details

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