Home LiteratureArticle Details
PMID: 266201 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Absence of a measurable G2 phase in two Chinese hamster cell lines.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 74 ·No. 4 ·1977-04-00 ·Pages 1622-5

Liskay RM

Abstract

Evidence is presented that demonstrates the absence of a measurable G2 phase in the cell cycles of two sublines of the Chinese hamster lung fibroblast V79. One of the sublines, in addition, lacks a detectable G1 phase, thereby possessing a cell cycle comprised of simply two phases, DNA synthesis (S) and mitosis (M).

MeSH Terms
Animals Cell Division Cell Line Cricetinae DNA Replication Fibroblasts Kinetics Lung Thymidine/metabolism Time Factors
Chemicals
Thymidine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Liskay R M
References (11)
11 references, click to expand
  1. DNA synthesis in individual L-strain mouse cells.
    Biochim Biophys Acta. 1960 Jan 29;37:406-19 PMID: 13833792
  2. CLONAL GROWTH OF MAMMALIAN CELLS IN A CHEMICALLY DEFINED, SYNTHETIC MEDIUM.
    Proc Natl Acad Sci U S A. 1965 Feb;53:288-93 PMID: 14294058
  3. LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. I. A METHOD FOR LOCALIZING METABOLIC EVENTS WITHIN THE LIFE CYCLE, AND ITS APPLICATION TO THE ACTION OF COLCEMIDE AND SUBLETHAL DOSES OF X-IRRADIATION.
    Biophys J. 1963 Sep;3:379-97 PMID: 14062457
  4. Radiation response of mammalian cells grown in culture. 1. Repair of X-ray damage in surviving Chinese hamster cells.
    Radiat Res. 1960 Oct;13:556-93 PMID: 13726391
  5. Cell population kinetics in the intestinal epithelium of the mouse.
    Exp Cell Res. 1959 Jun;17(3):420-38 PMID: 13672199
  6. Observations on the chromosomes of Chinese hamster cells in tissue culture.
    J Natl Cancer Inst. 1958 Aug;21(2):393-425 PMID: 13576097
  7. The chromosomes of CHO, an aneuploid Chinese hamster cell line: G-band, C-band, and autoradiographic analyses.
    Chromosoma. 1973;41(2):129-44 PMID: 4120885
  8. Cell cycle analysis and X-chromosome inactivation in the developing mouse.
    Proc Natl Acad Sci U S A. 1976 May;73(5):1608-11 PMID: 1064031
  9. The effects of some amino acid analogs on mitosis and the cell cycle.
    Exp Cell Res. 1969 May;55(2):161-7 PMID: 5772110
  10. The absence of a detectable G1 phase in a cultured strain of Chinese hamster lung cell.
    J Cell Biol. 1967 Aug;34(2):684-6 PMID: 6035652
  11. Life cycle analysis of mammalian cells. 3. The inhibition of division in Chinese hamster cells by puromycin and actinomycin.
    Biophys J. 1966 Sep;6(5):567-81 PMID: 5970563
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.74.4.1622
Published
1977-04-00
Pages
1622-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC430843
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.74.4.1622 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2