Home LiteratureArticle Details

PMID: 2677740 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.

Nature ·Vol. 341 ·No. 6240 ·1989-09-28 ·Pages 299-303

Horikoshi M, Wang CK, Fujii H, Cromlish JA, Weil PA, Roeder RG

Abstract

The TATA sequence-binding factor TFIID plays a central role both in promoter activation by RNA polymerase II and other common initiation factors, and in promoter regulation by gene-specific factors. The sequence of yeast TFIID, which seems to be encoded by a single gene, contains interesting structural motifs that are possibly involved in these functions, and is similar to sequences of bacterial sigma factors.

MeSH Terms

Amino Acid Sequence Base Sequence Chromosomes, Fungal Cloning, Molecular DNA, Fungal/genetics Gene Expression Genes Genes, Fungal Molecular Sequence Data Promoter Regions, Genetic Protein Binding RNA, Messenger/analysis,genetics Saccharomyces cerevisiae/genetics Sequence Homology, Nucleic Acid Transcription Factor TFIID Transcription Factors/genetics,metabolism Transcription, Genetic

Chemicals

DNA, Fungal RNA, Messenger Transcription Factor TFIID Transcription Factors

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Horikoshi M

Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.

Wang C K

Fujii H

Cromlish J A

Weil P A

Roeder R G

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/341299a0

Published

1989-09-28

Pages

299-303

Language

English

Region

England

NLM ID

0410462

Subset

Databases

GENBANK

X16860

External Links

PubMed source DOI: 10.1038/341299a0 View journal details

Analysis Services

Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box.

Contact

WeChat Official Account