Molecular Detection of Rickettsia felis in Humans, Cats, and Cat Fleas in Bangladesh, 2013-2014.

Vector borne and zoonotic diseases (Larchmont, N.Y.) ·Vol. 16 ·No. 5 ·2016-00-00 ·页码 356-8

Ahmed R, Paul SK, Hossain MA, Ahmed S, Mahmud MC, Nasreen SA, Ferdouse F, Sharmi RH, Ahamed F, Ghosh S, Urushibara N, Aung MS, Kobayashi N

Abstract

High prevalence of Rickettsia felis in patients with fever of unknown origin was revealed in the north-central Bangladesh from 2012 to 2013. Subsequently, in this study, prevalence of R. felis in cats and cat fleas (Ctenocephalides felis), together with febrile patients, was studied by PCR detection of 17 kDa antigen gene and DNA sequencing. R. felis was detected in 28% (28/100) and 21% (14/68) of cat blood and cat flea samples, respectively, whereas 42% (21/50) of patients were positive for R. felis. R. felis-positive cat fleas were detected at significantly higher rate on R. felis-positive cats. The results suggested a potential role of cats and cat fleas for transmission of R. felis to humans in Bangladesh.

Keywords

Bangladesh Rickettsia felis cat cat flea

MeSH 主题词

Animals Bangladesh/epidemiology Cat Diseases/epidemiology,microbiology Cats DNA, Bacterial/genetics Humans Rickettsia Infections/epidemiology,microbiology,veterinary Rickettsia felis/genetics,isolation & purification Siphonaptera/microbiology

化学物质

DNA, Bacterial

作者与单位

共 13 位作者，点击展开单位 / ORCID

Ahmed Rajib

1 Department of Microbiology, Mymensingh Medical College , Mymensingh, Bangladesh . | 2 Department of Biochemistry, Manikganj Medical College , Manikganj, Bangladesh .

Paul Shyamal Kumar