[Changes in the natural killer activity of lymphocytes in peripheral blood of patients with purulent-septic diseases under the effect of extracorporeal perfusion of pig spleen sections].

23 patients with pyo-septic diseases resistant to conservative therapy were treated by extracorporeal perfusion of xenospleen (EPXS). In 17 patients on EPXS a persistent detoxicating effect was achieved. 6 patients died. EPXS procedure was accompanied by a drop in medium-molecular lipid blood level and normalization of natural killer activity that was decreased considerably prior to EPXS. It is concluded that EPXS has a normalizing effect on the natural killer activity, which may be essential for resistance to infectious complications.