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PMID: 2712546 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Ciprofloxacin for methicillin-resistant Staphylococcus aureus infections.

Antimicrobial agents and chemotherapy ·Vol. 33 ·No. 1 ·1989-01-00 ·Pages 128-30

Piercy EA, Barbaro D, Luby JP, Mackowiak PA

Abstract

Thirty-seven patients with methicillin-resistant Staphylococcus aureus infections and/or colonization were treated with oral ciprofloxacin (750 mg twice a day). Clinical cure or improvement of infections occurred in 91% of the patients, and bacteriologic cure occurred in 60%. Ciprofloxacin therapy suppressed methicillin-resistant S. aureus colonization in 55% of the patients. Ciprofloxacin-resistant strains emerged in 6 of the 37 patients.

MeSH Terms
Ciprofloxacin/therapeutic use Drug Resistance, Microbial Humans Methicillin/pharmacology Penicillin Resistance Staphylococcal Infections/drug therapy Staphylococcus aureus/drug effects
Chemicals
Ciprofloxacin Methicillin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Piercy E A
Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas 75235.
Barbaro D
Luby J P
Mackowiak P A
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13 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1989-01-00
Pages
128-30
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC171438
Subset
IM
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