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PMID: 2719620 Published · ppublish English Journal Article

Bias in correlations from selected samples of relatives: the effects of soft selection.

Behavior genetics ·Vol. 19 ·No. 2 ·1989-03-00 ·Pages 163-9

Neale MC, Eaves LJ, Kendler KS, Hewitt JK

Abstract

Martin and Wilson (1982) describe two forms of sampling bias in twin studies. One is "hard selection," where individuals above a threshold participate, and those below do not. The second is "soft selection," where the probability of including a pair of relatives varies over the range of the character. We present an alternative model of soft selection which has strikingly different consequences for the resemblance between relatives. In general, the softer the threshold, the more the correlation resembles that in the underlying population. Results are presented where the probability of selection equals the cumulative distribution function of a normal distribution with 10% of the variance of the selected variable. In these circumstances, soft selection usually leads to less severely attenuated correlations than truncate selection.

MeSH Terms
Genetics, Behavioral Humans Probability Sampling Studies Twins/psychology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Neale M C
Eaves L J
Kendler K S
Hewitt J K
References (4)
4 references, click to expand
  1. Recruitment bias in twin research: the rule of two-thirds reconsidered.
    Behav Genet. 1987 Jul;17(4):343-62 PMID: 3675526
  2. Volunteer bias in twin research: the rule of two-thirds.
    Soc Biol. 1978 Spring;25(1):1-9 PMID: 565949
  3. Altruism and genetics.
    Acta Genet Med Gemellol (Roma). 1984;33(2):265-71 PMID: 6540960
  4. Bias in the estimation of heritability from truncated samples of twins.
    Behav Genet. 1982 Jul;12(4):467-72 PMID: 6890347
Article Info
Journal
Behavior genetics
Abbr.
Behav Genet
ISSN
0001-8244
Published
1989-03-00
Pages
163-9
Language
English
Region
United States
NLM ID
0251711
Subset
IM
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