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PMID: 272647 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Geometric packing constraints in egg phosphatidylcholine vesicles.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 75 ·No. 1 ·1978-01-00 ·Pages 308-10

Huang C, Mason JT

Abstract

This investigation presents a quantitative analysis of the asymmetric transmembrane lipid packing geometry in egg phosphatidylcholine vesicles. The analysis uses hydrodynamic and nuclear magnetic resonance data obtained for homogeneous egg phosphatidylcholine vesicles and demonstrates that the average area per lipid head group and effective length of the lipid are greater on the outer monolayer than on the inner monolayer of the egg phosphatidylcholine vesicle. Results also indicate that the bilayer of the egg phosphatidylcholine vesicles has an asymmetrical interface through its center.

MeSH Terms

Animals Chickens Eggs Liposomes Magnetic Resonance Spectroscopy Membranes, Artificial Molecular Conformation Phosphatidylcholines Water

Chemicals

Liposomes Membranes, Artificial Phosphatidylcholines Water

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Huang C

Mason J T

References (15)

15 references, click to expand

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Structure in the polar head region of phospholipid bilayers: A 31P [1H] nuclear Overhauser effect study.
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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.75.1.308

Published

1978-01-00

Pages

308-10

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC411236

Subset

External Links

PubMed source DOI: 10.1073/pnas.75.1.308 PMC Full Text View journal details

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