Home LiteratureArticle Details
PMID: 27791179 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Comment

It takes a genome to understand a village: Population scale precision medicine.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 113 ·No. 44 ·2016-00-01 ·Pages 12344-12346

Butte AJ

Abstract

暂无摘要

MeSH Terms
Demography Genome Humans Precision Medicine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Butte Atul J ORCID
Institute for Computational Health Sciences, University of California, San Francisco, CA 94158 [email protected].
Conflict of Interest

The author has a minor investment in Illumina and other biotech companies. He is a cofounder and consultant to Personalis, a company offering services in medical genome sequencing. The author is a scientific advisor to Geisinger Health System. In the past, he has been a consultant to Regeneron.

References (14)
14 references, click to expand
  1. Circulating mutant DNA to assess tumor dynamics.
    Nat Med. 2008 Sep;14(9):985-90 PMID: 18670422
  2. Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.
    N Engl J Med. 2016 Mar 24;374(12):1123-33 PMID: 26933753
  3. Genomic analyses inform on migration events during the peopling of Eurasia.
    Nature. 2016 Oct 13;538(7624):238-242 PMID: 27654910
  4. Accelerating scientific publication in biology.
    Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13439-46 PMID: 26508643
  5. Targeted capture and massively parallel sequencing of 12 human exomes.
    Nature. 2009 Sep 10;461(7261):272-6 PMID: 19684571
  6. Analysis of protein-coding genetic variation in 60,706 humans.
    Nature. 2016 Aug 17;536(7616):285-91 PMID: 27535533
  7. Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.
    Genet Med. 2011 Mar;13(3):255-62 PMID: 21173700
  8. Deep sequencing of 10,000 human genomes.
    Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11901-11906 PMID: 27702888
  9. Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood.
    Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16266-71 PMID: 18838674
  10. The sequence of the human genome.
    Science. 2001 Feb 16;291(5507):1304-51 PMID: 11181995
  11. Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway.
    Genet Med. 2014 Oct;16(10):751-8 PMID: 24651605
  12. OpenFDA: an innovative platform providing access to a wealth of FDA's publicly available data.
    J Am Med Inform Assoc. 2016 May;23(3):596-600 PMID: 26644398
  13. Clinical assessment incorporating a personal genome.
    Lancet. 2010 May 1;375(9725):1525-35 PMID: 20435227
  14. Actionable diagnosis of neuroleptospirosis by next-generation sequencing.
    N Engl J Med. 2014 Jun 19;370(25):2408-17 PMID: 24896819
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
1091-6490
Published
2016-00-01
Epub
2016-00-19
Pages
12344-12346
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC5098617
Subset
IM
Grants
NIH HHS · OT2 OD024611 · United States
Corrections
CommentOn
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]