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PMID: 2816136 Published · ppublish ger Case Reports English Abstract Journal Article

[The question of medullomyoblastoma].

Zur Frage des Medullomyoblastoms.

Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie ·Vol. 135 ·No. 5 ·1989-00-00 ·Pages 445-55

Patt S, Oppel F, Cervós-Navarro J

Abstract

We report a 7 year old female presenting with a primary sarcoma of the frontal cortex, spinal cord metastases, and a cerebellar tumor. The latter was comprised of undifferentiated small cells and a component resembling rhabdomyosarcoma. On formal grounds it could be diagnosed either as medullomyoblastoma or rhabdomyosarcoma. At the ultrastructural level the tumor appeared more typical for a medullomyoblastoma but it seem highly improbable that both (rare) tumors appeared simultaneously by coincidence. Rather, we assume that we are dealing with a metastasis of the sarcoma with differentiation towards rhabdomyosarcoma. The apparent ability of a sarcoma to imitate morphological features of medullomyoblastoma in the cerebellum is further proof of the fact that nosological differentiation of both tumors remains a problem. Our findings did not corroborate the concept of medullomyoblastoma as a separate nosological entity.

MeSH Terms
Brain Neoplasms/pathology,ultrastructure Cerebellar Neoplasms/pathology,secondary,ultrastructure Child Diagnosis, Differential Female Frontal Lobe Humans Medulloblastoma/pathology,secondary,ultrastructure Rhabdomyosarcoma/pathology,secondary,ultrastructure Sarcoma/pathology,secondary,ultrastructure Spinal Cord Neoplasms/pathology,secondary,ultrastructure
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Patt S
Institut für Neuropathologie, Freien Universität Berlin.
Oppel F
Cervós-Navarro J
Article Info
Journal
Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie
Abbr.
Zentralbl Allg Pathol
ISSN
0044-4030
Published
1989-00-00
Pages
445-55
Language
ger
Region
Germany
NLM ID
9105593
Subset
IM
External Links
PubMed source
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