Abstract
Mutations which prevent absorption of the bacteriophage K20 to Escherichia coli K-12 were selected by using an altered OmpF protein which confers the ability to grow on maltodextrin in the absence of the LamB maltoporin. The mutations map in the rfa gene cluster and alter the structure of the lipopolysaccharide core.
MeSH Terms
Alleles
Anti-Bacterial Agents/pharmacology
Bacterial Outer Membrane Proteins/metabolism
Cell Membrane Permeability
Coliphages/metabolism
Escherichia coli/drug effects,genetics,growth & development
Genes, Bacterial
Genetic Linkage
Lipopolysaccharides/metabolism
Mutation
Phenotype
Polysaccharides/metabolism
Porins
Receptors, Virus/metabolism
Transduction, Genetic
Chemicals
Anti-Bacterial Agents
Bacterial Outer Membrane Proteins
Lipopolysaccharides
Polysaccharides
Porins
Receptors, Virus
maltoporins
maltodextrin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Silverman J A
Department of Molecular Biology, Princeton University, New Jersey 08544.
Benson S A
References (18)
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