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PMID: 2829800 Published · ppublish English Journal Article

Transcription from the pseudorabies virus genome during latent infection. Brief report.

Archives of virology ·Vol. 98 ·No. 1-2 ·1988-00-00 ·Pages 99-106

Rock DL, Hagemoser WA, Osorio FA, McAllister HA

Abstract

Trigeminal ganglia from swine latently infected with pseudorabies virus (PRV) were examined for the presence of PRV nucleic acids by in situ hybridization. Both viral DNA and RNA were detectable in latently infected neurons, indicating that the PRV genome is transcriptionally active during the latent phase of infection.

MeSH Terms
Animals DNA, Viral/analysis Ganglia/microbiology Herpesvirus 1, Suid/genetics Nucleic Acid Hybridization Pseudorabies/microbiology RNA, Viral/analysis Swine Transcription, Genetic Trigeminal Nerve/microbiology
Chemicals
DNA, Viral RNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Rock D L
Veterinary Medical Research Institute, College of Veterinary Medicine, Iowa State University Ames.
Hagemoser W A
Osorio F A
McAllister H A
References (20)
20 references, click to expand
  1. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
    J Mol Biol. 1977 Jun 15;113(1):237-51 PMID: 881736
  2. Detection of HSV-1 genome in central nervous system of latently infected mice.
    Nature. 1983 Apr 7;302(5908):523-5 PMID: 6300686
  3. In vivo and in vitro reactivation of latent pseudorabies virus in pigs born to vaccinated sows.
    Am J Vet Res. 1984 Mar;45(3):567-71 PMID: 6324622
  4. Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans.
    J Virol. 1986 Feb;57(2):446-55 PMID: 3003377
  5. Purification and buoyant density of infectious bovine rhinotracheitis virus.
    Proc Soc Exp Biol Med. 1976 Jan;151(1):132-5 PMID: 175368
  6. Continued expression of a poly(A)+ transcript of herpes simplex virus type 1 in trigeminal ganglia of latently infected mice.
    J Virol. 1987 May;61(5):1700-3 PMID: 3033297
  7. Detection of viral sequences of low reiteration frequency by in situ hybridization.
    Proc Natl Acad Sci U S A. 1978 Dec;75(12):6125-9 PMID: 216014
  8. Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor.
    Cell. 1978 Jul;14(3):725-31 PMID: 210957
  9. Spontaneous shedding of pseudorabies virus from a clinically recovered postparturient sow.
    J Am Vet Med Assoc. 1980 Jun 15;176(12):1345-7 PMID: 6253425
  10. Latent pseudorabies virus infection in swine detected by RNA-DNA hybridization.
    Am J Vet Res. 1979 Nov;40(11):1568-72 PMID: 230759
  11. Herpesvirus (pseudorabies virus) latency in swine: occurrence and physical state of viral DNA in neural tissues.
    Virology. 1986 Dec;155(2):600-13 PMID: 3024403
  12. A new method for the isolation of herpes simplex virus type 2 DNA.
    Virology. 1976 Oct 1;74(1):256-8 PMID: 185791
  13. Occurrence and reactivation of latent Aujeszky's disease virus following challenge in previously vaccinated pigs.
    Arch Virol. 1983;75(1-2):29-41 PMID: 6299245
  14. Induced latency in pseudorabies vaccinated pigs.
    Can J Comp Med. 1981 Jan;45(1):56-9 PMID: 6268266
  15. Detection of bovine herpesvirus type 1 RNA in trigeminal ganglia of latently infected rabbits by in situ hybridization.
    J Gen Virol. 1986 Nov;67 ( Pt 11):2515-20 PMID: 3023537
  16. RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected neurons.
    Science. 1987 Feb 27;235(4792):1056-9 PMID: 2434993
  17. Persistence of pseudorabies virus in infected swine.
    J Am Vet Med Assoc. 1980 May 15;176(10 Pt 1):998-1000 PMID: 6247312
  18. Latent pseudorabies virus infection in pigs.
    Acta Virol. 1976 Jun;20(3):208-14 PMID: 9801
  19. Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy.
    J Histochem Cytochem. 1974 Dec;22(12):1077-83 PMID: 4374474
  20. Localization of herpes simplex virus in the trigeminal and olfactory systems of the mouse central nervous system during acute and latent infections by in situ hybridization.
    Lab Invest. 1984 Jul;51(1):27-38 PMID: 6330452
Article Info
Journal
Archives of virology
Abbr.
Arch Virol
ISSN
0304-8608
Published
1988-00-00
Pages
99-106
Language
English
Region
Austria
NLM ID
7506870
Subset
IM
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