Developmental analysis of two wing scalloping mutantsct 6 andBx J ofDrosophila melanogaster.

Wilhelm Roux's archives of developmental biology ·Vol. 178 ·No. 3 ·1975-09-00 ·Pages 233-245

Santamaria P, Garcia-Bellido A

Abstract

The mutantscut 6 (ct6) andBeadex of Jollos (Bx J) show nicks in the wing margins as well as other malformations in different regions of the body. Clonal analysis of the wing disk's development in these mutants indicates that massive cell loss occurs during the third larval instar. Morphogenetic mosaics, originating from mitotic recombination, reveal a non-autonomous behaviour of both mutant and wild-type cells. X-rays applied during the third larval instar produce phenocopies of these mutants. A clonal and a genetic analysis of these phenocopies has been carried out.The hypothesis that scalloping mutants such asct 6, BxJ and others, as well as X-rays, affect properties of cellular interaction, such as cell adhesivity or cohesion, is discussed. Morphogenetic mosaics in the wing margin suggest that the differentiation of the marginal cuticular elements requires the interaction of the cells of the ventral and dorsal surfaces of the wing.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Santamaria Pedro

Centro de Investigaciones Biológicas, Instituto de genética y antropología, C.S.I.C., Velázquez, 144, Madrid 6, Spanien.

Garcia-Bellido Antonio

Centro de Investigaciones Biológicas, Instituto de genética y antropología, C.S.I.C., Velázquez, 144, Madrid 6, Spanien.

References (11)

11 references, click to expand

Wilhelm Roux Arch Entwickl Mech Org. 1936 Mar;134(1):147-165 PMID: 28354858
The Beadex Locus in Drosophila Melanogaster: On the Nature of the Mutants Bx and Bx.
Genetics. 1953 Jan;38(1):91-105 PMID: 17247425
Fine structure ofDrosophila wing imaginal discs during early stages of metamorphosis.
Wilhelm Roux Arch Entwickl Mech Org. 1969 Dec;163(4):375-390 PMID: 28304478
Cellular degeneration in the production of some mutant phenotypes in Drosophila melanogaster.
Mol Gen Genet. 1969;103(4):363-79 PMID: 4979601
[Roentgen mosaic spots & defective mutations at the eye of Drosophila & the evolutive physiology of the eye].
Z Indukt Abstamm Vererbungsl. 1957;88(3):333-73 PMID: 13496909
[Effect of X-rays on the development of male genital imaginal disc in Drosophila melanogaster and investigation of recovery by cell-clone analysis].
Biophysik. 1972;8(2):158-88 PMID: 4623454
Developmental compartmentalisation of the wing disk of Drosophila.
Nat New Biol. 1973 Oct 24;245(147):251-3 PMID: 4518369
Behaviour in aggregates of irradiated imaginal disk cells ofDrosophila.
Wilhelm Roux Arch Entwickl Mech Org. 1973 Sep;172(3):187-195 PMID: 28305244
Parameters of the wing imaginal disc development of Drosophila melanogaster.
Dev Biol. 1971 Jan;24(1):61-87 PMID: 5001010
The influence of the quantity and quality of chromosomal material on the size of the cells in drosophila melanogaster.
Wilhelm Roux Arch Entwickl Mech Org. 1929 Apr;115(3):363-379 PMID: 28353864
The ultrastructure of the developing leg ofDrosophila melanogaster.
Wilhelm Roux Arch Entwickl Mech Org. 1970 Mar;166(1):1-44 PMID: 28304536

Article Info

Journal

Wilhelm Roux's archives of developmental biology

Abbr.

Wilehm Roux Arch Dev Biol

ISSN

0340-0794

DOI

10.1007/BF00848431

Published

1975-09-00

Pages

233-245

Language

English

Region

Germany

NLM ID

7508796

External Links

PubMed source DOI: 10.1007/BF00848431

Analysis Services

Developmental analysis of two wing scalloping mutantsct 6 andBx J ofDrosophila melanogaster.

Contact

WeChat Official Account