Postnatal transmission of AIDS-associated retrovirus from mother to infant.

Lancet (London, England) ·Vol. 1 ·No. 8434 ·1985-04-20 ·Pages 896-8

Ziegler JB, Cooper DA, Johnson RO, Gold J

Abstract

The third child of a previously healthy woman was delivered by caesarean section. Because of intraoperative blood loss, a blood transfusion was given after the delivery. The baby was breast-fed for 6 weeks. One unit of blood came from a male in whom the acquired immunodeficiency syndrome (AIDS) developed 13 months later. On recall, the mother proved to have lymphadenopathy, serum antibody to the AIDS virus, and a reduced T4/T8 ratio. The infant, who failed two thrive and had atopic eczema from 3 months, has likewise proved to have antibody to the AIDS virus. Since his mother was transfused after his birth, he is presumed to have been infected via breast milk or by way of some other form of close contact with his mother.

Keywords

Acquired Immunodeficiency Syndrome Age Factors Australia Biology Breast Feeding Case Studies Demographic Factors Developed Countries Developing Countries Diseases Family And Household Family Characteristics Family Relationships Health Hematological Effects Hiv Infections Human Milk Infant Infant Nutrition Lactation Maternal Physiology Mothers Nutrition Oceania Parents Physiology Population Population Characteristics Viral Diseases Youth

MeSH Terms

Acquired Immunodeficiency Syndrome/etiology,transmission Adult Antibodies, Viral/analysis Deltaretrovirus/immunology Female HIV Antibodies Humans Infant Male Milk, Human/microbiology Postpartum Period Pregnancy Retroviridae Infections/etiology,transmission Transfusion Reaction

Chemicals

Antibodies, Viral HIV Antibodies

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Ziegler J B

Cooper D A

Johnson R O

Gold J

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(85)91673-3

Published

1985-04-20

Pages

896-8

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/s0140-6736(85)91673-3 View journal details

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Postnatal transmission of AIDS-associated retrovirus from mother to infant.

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