Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.

6-Cyano-7-nitroquinoxaline-2,3-dione Action Potentials/drug effects Animals Aspartic Acid/analogs & derivatives,pharmacology Binding, Competitive Cell Membrane/metabolism Cerebral Cortex/metabolism Ibotenic Acid/analogs & derivatives,metabolism Kainic Acid/metabolism Ketamine/pharmacology N-Methylaspartate Neurons/physiology Piperazines/metabolism Quinoxalines/pharmacology Rats Receptors, AMPA Receptors, Drug/drug effects,metabolism Receptors, Glutamate Receptors, Kainic Acid Receptors, N-Methyl-D-Aspartate Receptors, Neurotransmitter/drug effects,metabolism Spinal Cord/physiology alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

Piperazines Quinoxalines Receptors, AMPA Receptors, Drug Receptors, Glutamate Receptors, Kainic Acid Receptors, N-Methyl-D-Aspartate Receptors, Neurotransmitter Ibotenic Acid Aspartic Acid FG 9041 N-Methylaspartate Ketamine 6-Cyano-7-nitroquinoxaline-2,3-dione alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid Kainic Acid