Abstract
In Alcaligenes eutrophus CH34, resistance to chromate is plasmid determined, inducible, and based on decreased net accumulation of the metal anion. Plasmid-encoded resistances to zinc, cadmium, cobalt, and nickel are resulting from inducible, energy-dependent cation efflux systems.
MeSH Terms
Alcaligenes/drug effects,genetics,metabolism
Cadmium/metabolism,pharmacology
Chromates/pharmacology
Cobalt/metabolism,pharmacology
Drug Resistance, Microbial/genetics
Kinetics
Nickel/metabolism
R Factors
Zinc/metabolism,pharmacology
Chemicals
Chromates
Cadmium
Cobalt
Nickel
Zinc
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Nies D H
Department of Microbiology and Immunology, College of Medicine, University of Illinois, Chicago 60680.
Silver S
References (13)
13 references, click to expand
-
Inorganic salts resistance associated with a lactose-fermenting plasmid in Streptococcus lactis.
J Bacteriol. 1977 Apr;130(1):257-65
PMID: 404284
-
Cation transport alteration associated with plasmid-determined resistance to cadmium in Staphylococcus aureus.
Antimicrob Agents Chemother. 1978 Dec;14(6):856-65
PMID: 742873
-
Penicillinase plasmids of Staphylococcus aureus: restriction-deletion maps.
Plasmid. 1979 Jan;2(1):109-29
PMID: 314115
-
Energy-dependent efflux of cadmium coded by a plasmid resistance determinant in Staphylococcus aureus.
J Bacteriol. 1981 Aug;147(2):313-9
PMID: 7263609
-
Chromate resistance plasmid in Pseudomonas fluorescens.
J Bacteriol. 1983 Sep;155(3):1105-9
PMID: 6309741
-
Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals.
J Bacteriol. 1985 Apr;162(1):328-34
PMID: 3884593
-
Plasmid-determined cadmium resistance in Pseudomonas putida GAM-1 isolated from soil.
J Bacteriol. 1986 Jan;165(1):334-5
PMID: 3941050
-
Resistance to metals by Pseudomonas aeruginosa clinical isolates.
Microbios. 1986;48(196-197):159-63
PMID: 3099130
-
Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmid.
J Bacteriol. 1987 Aug;169(8):3853-6
PMID: 3112130
-
Cloning of plasmid genes encoding resistance to cadmium, zinc, and cobalt in Alcaligenes eutrophus CH34.
J Bacteriol. 1987 Oct;169(10):4865-8
PMID: 2820947
-
Active-site-specific zinc-depleted and reconstituted cobalt(II) human-liver alcohol dehydrogenase. Preparation, characterization and complexation with NADH and trans-4-(N,N-dimethylamino)-cinnamaldehyde.
Eur J Biochem. 1988 Apr 15;173(2):275-80
PMID: 3360008
-
Inducible and constitutive expression of pMOL28-encoded nickel resistance in Alcaligenes eutrophus N9A.
J Bacteriol. 1988 Sep;170(9):4188-93
PMID: 3410828
-
Plasmid-mediated heavy metal resistances.
Annu Rev Microbiol. 1988;42:717-43
PMID: 3060006