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PMID: 2924136 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

GABAergic septohippocampal neurons contain parvalbumin.

Brain research ·Vol. 478 ·No. 2 ·1989-01-30 ·Pages 375-81

Freund TF

Abstract

Septal axons were visualized in the hippocampus by anterograde transport of Phaseolus vulgaris leucoagglutinin (PHAL) injected into the medial septal region, which contains large numbers of parvalbumin (PV)-immunoreactive somata. A proportion of the PHAL-labelled afferents in the hippocampus were shown to be immunoreactive for PV by immunostaining alternate sections. This population of septohippocampal axons alone was found to be immunoreactive for gamma-aminobutyric acid (GABA) following post-embedding immunogold staining of ultrathin sections cut from the same material.

MeSH Terms
Animals Female Hippocampus/cytology,metabolism Immunohistochemistry Muscle Proteins/metabolism Parvalbumins/metabolism Phytohemagglutinins Rats Rats, Inbred Strains Septal Nuclei/cytology,metabolism gamma-Aminobutyric Acid/metabolism
Chemicals
Muscle Proteins Parvalbumins Phytohemagglutinins gamma-Aminobutyric Acid
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Freund T F
MRC Anatomical Neuropharmacology Unit, Department of Pharmacology, Oxford, U.K.
Article Info
Journal
Brain research
Abbr.
Brain Res
ISSN
0006-8993
Published
1989-01-30
Pages
375-81
Language
English
Region
Netherlands
NLM ID
0045503
Subset
IM
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