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PMID: 2925488 Published · ppublish English Journal Article

Treatment and prognostic factors in lymphoma in cats: 103 cases (1977-1981).

Journal of the American Veterinary Medical Association ·Vol. 194 ·No. 5 ·1989-03-01 ·页码 696-702

Mooney SC, Hayes AA, MacEwen EG, Matus RE, Geary A, Shurgot BA

Abstract

The records of 103 cats with lymphoma that underwent chemotherapy were reviewed. Diagnosis was confirmed by cytologic or histopathologic examination of appropriate tissue specimens. Sixty-four cats (62%) had a complete response to chemotherapy (median survival time, 7 months); 21 cats (20%) had a partial response (median survival time, 2.5 months); and 18 cats had a minimal response (median survival time, 1.5 months). Seventy-seven cats (75%) died of recurrent or progressive lymphoma, 9 cats died of feline leukemia-related anemia, 13 cats died of unrelated causes, and 4 cats were alive. Stage of disease was significantly (P = 0.009) related to response to treatment, and stage of disease and FeLV status were both significantly (P = 0.002 and P less than 0.001, respectively) related to survival.

MeSH 主题词
Animals Antineoplastic Combined Chemotherapy Protocols/therapeutic use Asparaginase/administration & dosage Cat Diseases/drug therapy Cats Cyclophosphamide/administration & dosage Female Lymphoma/drug therapy,veterinary Male Methotrexate/administration & dosage Prednisone/administration & dosage Prognosis Retrospective Studies Vincristine/administration & dosage
化学物质
Vincristine Cyclophosphamide Asparaginase Prednisone Methotrexate
作者与单位
共 6 位作者,点击展开单位 / ORCID
Mooney S C
Donaldson-Atwood Cancer Clinic, Animal Medical Center, New York, NY 10021.
Hayes A A
MacEwen E G
Matus R E
Geary A
Shurgot B A
Article Info
Journal
Journal of the American Veterinary Medical Association
Abbr.
J Am Vet Med Assoc
ISSN
0003-1488
Published
1989-03-01
页码
696-702
Language
English
Country/Region
United States
NLM ID
7503067
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