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PMID: 293128 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A maximum likelihood map of chromosome 1.

American journal of human genetics ·Vol. 31 ·No. 6 ·1979-11-00 ·Pages 680-96

Rao DC, Keats BJ, Lalouel JM, Morton NE, Yee S

Abstract

Thirteen loci are mapped on chromosome 1 from genetic evidence. The maximum likelihood map presented permits confirmation that Scianna (SC) and a fourteenth locus, phenylketonuria (PKU), are on chromosome 1, although the location of the latter on the PGM1-AMY segment is uncertain. Eight other controversial genetic assignments are rejected, providing a practical demonstration of the resolution which maximum likelihood theory brings to mapping.

MeSH Terms
Chromosome Mapping Chromosomes, Human, 1-3 Female Genetic Linkage Genetic Markers Humans Male Phenylketonurias/genetics Polymorphism, Genetic
Chemicals
Genetic Markers
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Rao D C
Keats B J
Lalouel J M
Morton N E
Yee S
References (15)
15 references, click to expand
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Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1979-11-00
Pages
680-96
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1686048
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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