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PMID: 29313269 Published · ppublish English Case Reports Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Patient-Specific Modeling of Hemodynamics: Supporting Surgical Planning in a Fontan Circulation Correction.

Journal of cardiovascular translational research ·Vol. 11 ·No. 2 ·2018-00-00 ·页码 145-155

van Bakel TMJ, Lau KD, Hirsch-Romano J, Trimarchi S, Dorfman AL, Figueroa CA

Abstract

Computational fluid dynamics (CFD) is a modeling technique that enables calculation of the behavior of fluid flows in complex geometries. In cardiovascular medicine, CFD methods are being used to calculate patient-specific hemodynamics for a variety of applications, such as disease research, noninvasive diagnostics, medical device evaluation, and surgical planning. This paper provides a concise overview of the methods to perform patient-specific computational analyses using clinical data, followed by a case study where CFD-supported surgical planning is presented in a patient with Fontan circulation complicated by unilateral pulmonary arteriovenous malformations. In closing, the challenges for implementation and adoption of CFD modeling in clinical practice are discussed.

Keywords
Computational fluid dynamics Hemodynamics Patient-specific modeling Pulmonary arteriovenous malformations Single ventricle Surgical planning
MeSH 主题词
Adolescent Clinical Decision-Making Computed Tomography Angiography Coronary Angiography/methods Female Fontan Procedure/adverse effects,methods Heart Defects, Congenital/diagnostic imaging,pathology,physiopathology,surgery Hemodynamics Humans Models, Cardiovascular Patient Selection Patient-Centered Care/methods Patient-Specific Modeling Predictive Value of Tests Surgery, Computer-Assisted/adverse effects,methods Time-to-Treatment Ventricular Function
作者与单位
共 6 位作者,点击展开单位 / ORCID
van Bakel Theodorus M J ORCID
Department of Surgery, University of Michigan, Ann Arbor, MI, USA. [email protected].
Lau Kevin D
Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
Hirsch-Romano Jennifer
University of Michigan C.S. Mott Children's Hospital Congenital Heart Center, Ann Arbor, MI, USA.
Trimarchi Santi
Policlinico San Donato IRCCS, Thoracic Aortic Research Center, San Donato Milanese, Italy.
Dorfman Adam L
University of Michigan C.S. Mott Children's Hospital Congenital Heart Center, Ann Arbor, MI, USA.
Figueroa C Alberto
Department of Surgery, University of Michigan, Ann Arbor, MI, USA. | Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Article Info
Journal
Journal of cardiovascular translational research
Abbr.
J Cardiovasc Transl Res
ISSN
1937-5395
Corresponding email
Published
2018-00-00
电子出版
2018-00-08
页码
145-155
Language
English
Country/Region
United States
NLM ID
101468585
基金资助
FP7 Ideas: European Research Council · 307532 · International
National Science Foundation · 1531752 · International
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