Home LiteratureArticle Details

PMID: 2937721 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

MRC OX-52: a rat T-cell antigen.

Immunology ·Vol. 57 ·No. 4 ·1986-04-00 ·Pages 527-31

Robinson AP, Puklavec M, Mason DW

Abstract

A mouse monoclonal antibody MRC OX-52 has been shown to label rat T lymphocytes and thymocytes. The molecule precipitated by this antibody from both thymocytes and T lymphocytes had a two-chain structure of 120,000 MW and 95,000 MW.

MeSH Terms

Animals Antibodies, Monoclonal/immunology Antigens, Surface/analysis Immunoenzyme Techniques Lymphocyte Culture Test, Mixed Mice Mice, Inbred BALB C Molecular Weight Rats Rats, Inbred Strains T-Lymphocytes/immunology Thymus Gland/immunology

Chemicals

Antibodies, Monoclonal Antigens, Surface

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Robinson A P

Puklavec M

Mason D W

References (22)

22 references, click to expand

Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.
J Immunol. 1985 Sep;135(3):1922-8 PMID: 2410507
MRC OX-19: a monoclonal antibody that labels rat T lymphocytes and augments in vitro proliferative responses.
Eur J Immunol. 1984 Mar;14(3):260-7 PMID: 6231186
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.
Nature. 1970 Aug 15;227(5259):680-5 PMID: 5432063
The lymphocyte surface. II. Separation of Fc receptor, C'3 receptor and surface immunoglobulin-bearing lymphocytes.
Proc R Soc Lond B Biol Sci. 1974 Aug 27;187(1086):65-81 PMID: 4153865
Differences in the surface proteins of mouse B and T cells.
Proc Natl Acad Sci U S A. 1975 Jan;72(1):157-61 PMID: 47173
Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.
Eur J Immunol. 1976 Jul;6(7):511-9 PMID: 825377
Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.
Cell. 1977 Nov;12(3):663-73 PMID: 303545
T-lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody.
J Exp Med. 1978 Sep 1;148(3):664-73 PMID: 29936
The predominant heavily glycosylated glycoproteins at the surface of rat lymphoid cells are differentiation antigens.
Eur J Immunol. 1978 Dec;8(12):832-9 PMID: 310389
Identification of Ia glycoproteins in rat thymus and purification from rat spleen.
Eur J Immunol. 1979 Jun;9(6):426-33 PMID: 315315
OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.
J Immunol. 1980 Jun;124(6):2708-13 PMID: 6966296
The kinetics of antibody binding to membrane antigens in solution and at the cell surface.
Biochem J. 1980 Apr 1;187(1):1-20 PMID: 6967725
The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.
Immunology. 1981 Apr;42(4):593-600 PMID: 7016746
A repopulation assay for B and T lymphocyte stem cells employing radiation chimaeras.
Cell Tissue Kinet. 1981 Jul;14(4):445-64 PMID: 6973397
A novel human T cell antigen preferentially expressed on mature T cells and shared by both well and poorly differentiated B cell leukemias and lymphomas.
J Immunol. 1981 Sep;127(3):987-91 PMID: 6790625
Subsets of T cells in the rat mediating lethal graft versus-host disease.
Transplantation. 1981 Sep;32(3):222-6 PMID: 6974419
Different reticular elements in rat lymphoid tissue identified by localization of Ia, Thy-1 and MRC OX 2 antigens.
Immunology. 1981 Dec;44(4):727-36 PMID: 6119291
Lympho-stromal interactions in the thymus: medullary thymocytes react with I-A determinants on autochthonous thymic stimulator cells.
Eur J Immunol. 1982 Jan;12(1):51-9 PMID: 6174348
Characterization of nonlymphoid cells derived from rat peripheral lymph.
J Exp Med. 1983 Jun 1;157(6):1758-79 PMID: 6854208
Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells.
Nature. 1983 Aug 4-10;304(5925):445-7 PMID: 6224091
Molecular nature of the W3/25 and MRC OX-8 marker antigens for rat T lymphocytes: comparisons with mouse and human antigens.
Eur J Immunol. 1983 Oct;13(10):855-8 PMID: 6416869
Cytotoxic potential of different lymphoid cell populations against chromium-51 labelled tumour cells.
Clin Exp Immunol. 1969 Sep;5(3):273-84 PMID: 5810152

Article Info

Journal

Immunology

Abbr.

Immunology

ISSN

0019-2805

Published

1986-04-00

Pages

527-31

Language

English

Region

England

NLM ID

0374672

PMCID

PMC1453852

Subset

External Links

PubMed source PMC Full Text View journal details

Analysis Services

MRC OX-52: a rat T-cell antigen.

Contact

WeChat Official Account