Abstract
Information about the acute phase proteins (APP) response in cats naturally infected with hemoplasmas and in cats co-infected with different species of hemoplasmas is lacking. This study evaluated serum amyloid A (SAA), haptoglobin (Hp) and albumin in 48 cats naturally infected with hemoplasmas, including 25 with Candidatus Mycoplasma haemominutum and 23 co-infected with different hemoplasmas agents; and in 10 healthy control cats. Infected cats had significantly higher Hp and lower albumin than controls. Symptomatic cats had significantly higher SAA and Hp, and lower albumin than asymptomatic animals, and also than controls. Asymptomatic cats had significantly higher Hp than controls. Concentrations of APP were not significantly different between single infected and co-infected cats. According with these results, hemoplasmosis should be considered when alterations in APP are detected in diseased cats with compatible clinical signs. Furthermore, a subclinical infection should be considered in apparently healthy cats from endemic areas with increased Hp.
Keywords
Acute phase response
Albumin
Feline
Haptoglobin
Hemoplasma
Serum amyloid A
MeSH 主题词
Acute-Phase Proteins/analysis
Acute-Phase Reaction/immunology,veterinary
Animals
Case-Control Studies
Cat Diseases/blood,immunology,microbiology
Cats
Female
Haptoglobins/analysis
Male
Mycoplasma/immunology
Mycoplasma Infections/blood,immunology,veterinary
Serum Albumin/analysis
Serum Amyloid A Protein/analysis
化学物质
Acute-Phase Proteins
Haptoglobins
Serum Albumin
Serum Amyloid A Protein
作者与单位
共 7 位作者，点击展开单位 / ORCID
Vilhena Hugo
Vasco da Gama Research Center (CIVG), Department of Veterinary Medicine, Vasco da Gama Universitary School, Av. José R. Sousa Fernandes, 197 Lordemão, 3020-210, Coimbra, Portugal; Baixo Vouga Veterinary Hospital, EN1, 355, 3750-742, Águeda, Portugal; Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes and Alto Douro, Quinta de Prados, 5000-801, Vila Real, Portugal. Electronic address:
[email protected].
Tvarijonaviciute Asta
Department of Animal Medicine and Surgery, Autonomous University of Barcelona, Campus de la UAB, Plaça Cívica, s/n, 08193 Bellaterra, Barcelona, Spain; Interdisciplinary Laboratory of Clinical Analysis Interlab-UMU, University of Murcia, Ed. 16 Campus de Espinardo, 30100 Espinardo, Murcia, Spain. Electronic address:
[email protected].
Cerón José J
Interdisciplinary Laboratory of Clinical Analysis Interlab-UMU, University of Murcia, Ed. 16 Campus de Espinardo, 30100 Espinardo, Murcia, Spain. Electronic address:
[email protected].
Pastorinho M Ramiro
Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, R. Marquês de Ávila e Bolama, 6201-001 Covilhã, Portugal; Health Sciences Research Center (CICS-UBI), University of Beira Interior, R. Marquês de Ávila e Bolama, 6201-001 Covilhã, Portugal. Electronic address:
[email protected].
Martinez-Subiela Silvia
Interdisciplinary Laboratory of Clinical Analysis Interlab-UMU, University of Murcia, Ed. 16 Campus de Espinardo, 30100 Espinardo, Murcia, Spain. Electronic address:
[email protected].
Pastor Josep
Department of Animal Medicine and Surgery, Autonomous University of Barcelona, Campus de la UAB, Plaça Cívica, s/n, 08193 Bellaterra, Barcelona, Spain. Electronic address:
[email protected].
Silvestre-Ferreira Ana C
Animal and Veterinary Research Centre (CECAV), University of Trás-os-Montes and Alto Douro, Quinta de Prados, 5000-801, Vila Real, Portugal; Department of Veterinary Sciences, University of Trás-os-Montes e Alto Douro, Quinta de Prados, 5000-801, Vila Real, Portugal. Electronic address:
[email protected].
