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PMID: 2942105 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Bactericidal activity of ciprofloxacin against amikacin- and cefotaxime-resistant gram-negative bacilli and methicillin-resistant staphylococci.

Antimicrobial agents and chemotherapy ·Vol. 29 ·No. 6 ·1986-06-00 ·Pages 1098-100

Simberkoff MS, Rahal JJ

Abstract

The MICs and MBCs of ciprofloxacin were determined for clinical isolates of antibiotic-resistant aerobic bacteria. Decreased susceptibility to ciprofloxacin of cefotaxime- and amikacin-resistant Serratia marcescens and amikacin-resistant Pseudomonas aeruginosa strains were noted. The data suggest that ciprofloxacin susceptibility should be carefully monitored in treating patients with hospital-acquired bacterial infections.

MeSH Terms
Amikacin/pharmacology Cefotaxime/pharmacology Ciprofloxacin Cross Infection/microbiology Gram-Negative Bacteria/drug effects Humans Kanamycin/analogs & derivatives Methicillin/pharmacology Penicillin Resistance Quinolines/pharmacology Staphylococcus/drug effects
Chemicals
Quinolines Kanamycin Ciprofloxacin Amikacin Cefotaxime Methicillin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Simberkoff M S
Rahal J J
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20 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.29.6.1098
Published
1986-06-00
Pages
1098-100
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC180508
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.29.6.1098 PMC Full Text View journal details
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