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PMID: 2954542 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Nature of the subunits of the 6-phosphofructo-1-kinase isoenzymes from rat tissues.

The Biochemical journal ·Vol. 242 ·No. 3 ·1987-03-15 ·Pages 667-71

Dunaway GA, Kasten TP

Abstract

The nature of the PFK (6-phosphofructo-1-kinase) isoenzymes in many rat tissues was examined by immunological and chromatographic techniques and by measurement of their subunit compositions. It was revealed that, except for diaphragm and skeletal muscle, these complex isoenzymic populations contained different amounts of the three subunit types and were nearly tissue-specific. Apparently this tissue specificity is due to different concentrations of the tetramers, which in turn are controlled by the types and amounts of each subunit that are available to associate randomly.

MeSH Terms
Animals Electrophoresis, Polyacrylamide Gel Immunoelectrophoresis Isoenzymes Organ Specificity Phosphofructokinase-1 Proteins/analysis Rats Rats, Inbred Strains Tissue Distribution
Chemicals
Isoenzymes Proteins Phosphofructokinase-1
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Dunaway G A
Kasten T P
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23 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2420667
Published
1987-03-15
Pages
667-71
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1147763
Subset
IM
Grants
NICHD NIH HHS · HD 16666 · United States
External Links
PubMed source DOI: 10.1042/bj2420667 PMC Full Text View journal details
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