Home LiteratureArticle Details
PMID: 29548523 Published · ppublish English Case Reports Journal Article

Effects of nasal septum perforation repair on nasal airflow: An analysis using computational fluid dynamics on preoperative and postoperative three-dimensional models.

Auris, nasus, larynx ·Vol. 45 ·No. 5 ·2018-10-00 ·Pages 1020-1026

Nomura T, Ushio M, Kondo K, Kikuchi S

Abstract

The purpose of this research is to examine the changes in nasal airflow dynamics before and after the nasal perforation repair. Three dimensional (3D) models of the nasal cavity before and after septal perforation repair was reconstructed using preoperative and postoperative computed tomography (CT) images of a patient. The numerical simulation was carried out using ANSYS CFX V15.0. Pre- and post-operative models were compared by their velocity, pressure (P), pressure gradient (PG), wall shear (WS), shear strain rate (SSR) and turbulence kinetic energy (TKE) in three plains. In the post-operative state, the cross flows disappeared. In preoperative state, there were areas showing high PG, WS, SSR at the posterior border of the perforation, which exactly correspond to the area showing erosive mucosa on endoscopic inspection of the patient. In postoperative state, such high PG, WS and SSR areas disappeared. High TKEs also disappeared after surgery. The effects of septal perforation repair on airflow dynamics were evaluated using computer fluid dynamics (CFD). High WS, PG and SSR observed at the edge of the septal perforation may be related to the clinical symptom such as nasal bleeding and pain. TKE was considered to cause nasal symptom.

Keywords
Airflow evaluation Nasal septal perforation Numerical simulation
MeSH Terms
Endoscopy Female Humans Hydrodynamics Imaging, Three-Dimensional Middle Aged Nasal Cavity/diagnostic imaging Nasal Septal Perforation/diagnostic imaging,physiopathology,surgery Nasal Septum/diagnostic imaging Patient-Specific Modeling Postoperative Period Preoperative Period Pressure Tomography, X-Ray Computed
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Nomura Tsutomu
Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama, 380-8550, Japan. Electronic address: [email protected].
Ushio Munetaka
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Kondo Kenji
Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Kikuchi Shigeru
Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama, 380-8550, Japan.
Article Info
Journal
Auris, nasus, larynx
Abbr.
Auris Nasus Larynx
ISSN
1879-1476
Published
2018-10-00
Epub
2018-00-13
Pages
1020-1026
Language
English
Region
Netherlands
NLM ID
7708170
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]