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PMID: 2963095 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Photodynamic therapy.

Manyak MJ, Russo A, Smith PD, Glatstein E

Abstract

Photodynamic therapy (PDT) is an experimental cancer treatment modality that selectively destroys cancer cells by an interaction between absorbed light and a retained photosensitizing agent. This review discusses the basic components of photodynamic activity and examines the clinical applications of photodynamic therapy in cancer treatment. Treatment of superficial and early-stage malignancies is encouraging. Technologic advancement and further elucidation of the fundamental basis of photodynamic action should permit treatment of more advanced malignancies.

MeSH Terms
Fluorescence Hematoporphyrin Derivative Hematoporphyrins/therapeutic use Humans Neoplasms/drug therapy,pathology Photochemotherapy/trends Quality Control
Chemicals
Hematoporphyrins Hematoporphyrin Derivative
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Manyak M J
National Cancer Institute, Radiation Oncology Branch, Bethesda, MD 20892.
Russo A
Smith P D
Glatstein E
Article Info
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Abbr.
J Clin Oncol
ISSN
0732-183X
Published
1988-02-00
Pages
380-91
Language
English
Region
United States
NLM ID
8309333
Subset
IM
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