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PMID: 29858530 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Modeling hemodynamics in intracranial aneurysms: Comparing accuracy of CFD solvers based on finite element and finite volume schemes.

International journal for numerical methods in biomedical engineering ·Vol. 34 ·No. 9 ·2018-00-00 ·页码 e3111

Botti L, Paliwal N, Conti P, Antiga L, Meng H

Abstract

Image-based computational fluid dynamics (CFD) has shown potential to aid in the clinical management of intracranial aneurysms, but its adoption in the clinical practice has been missing, partially because of lack of accuracy assessment and sensitivity analysis. To numerically solve the flow-governing equations, CFD solvers generally rely on 2 spatial discretization schemes: finite volume (FV) and finite element (FE). Since increasingly accurate numerical solutions are obtained by different means, accuracies and computational costs of FV and FE formulations cannot be compared directly. To this end, in this study, we benchmark 2 representative CFD solvers in simulating flow in a patient-specific intracranial aneurysm model: (1) ANSYS Fluent, a commercial FV-based solver, and (2) VMTKLab multidGetto, a discontinuous Galerkin (dG) FE-based solver. The FV solver's accuracy is improved by increasing the spatial mesh resolution (134k, 1.1m, 8.6m, and 68.5m tetrahedral element meshes). The dGFE solver accuracy is increased by increasing the degree of polynomials (first, second, third, and fourth degree) on the base 134k tetrahedral element mesh. Solutions from best FV and dGFE approximations are used as baseline for error quantification. On average, velocity errors for second-best approximations are approximately 1 cm/s for a [0,125] cm/s velocity magnitude field. Results show that high-order dGFE provides better accuracy per degree of freedom but worse accuracy per Jacobian nonzero entry as compared with FV. Cross-comparison of velocity errors demonstrates asymptotic convergence of both solvers to the same numerical solution. Nevertheless, the discrepancy between underresolved velocity fields suggests that mesh independence is reached following different paths.

Keywords
discontinuous Galerkin method finite volume method high-order accurate hemodynamics intracranial aneurysm
MeSH 主题词
Blood Flow Velocity Finite Element Analysis Hemodynamics Humans Intracranial Aneurysm/physiopathology Models, Cardiovascular
作者与单位
共 5 位作者,点击展开单位 / ORCID
Botti Lorenzo ORCID
Department of Engineering and Applied Sciences, University of Bergamo, Bergamo, Italy.
Paliwal Nikhil
Toshiba Stroke and Vascular Research Center, University of Buffalo, Buffalo, NY, USA. | Department of Neurosurgery, University at Buffalo, Buffalo, NY, USA.
Conti Pierangelo
Department of Engineering and Applied Sciences, University of Bergamo, Bergamo, Italy.
Antiga Luca
Orobix SRL, Bergamo, Italy.
Meng Hui
Toshiba Stroke and Vascular Research Center, University of Buffalo, Buffalo, NY, USA. | Department of Neurosurgery, University at Buffalo, Buffalo, NY, USA. | Department of Mechanical and Aerospace Engineering, University of Buffalo, Buffalo, NY, USA. | Department of Biomedical Engineering, University at Buffalo, Buffalo, NY, USA.
Article Info
Journal
International journal for numerical methods in biomedical engineering
Abbr.
Int J Numer Method Biomed Eng
ISSN
2040-7947
Published
2018-00-00
电子出版
2018-00-20
页码
e3111
Language
English
Country/Region
England
NLM ID
101530293
基金资助
NCATS NIH HHS · UL1 TR001412 · United States
NINDS NIH HHS · R03 NS090193 · United States
NINDS NIH HHS · R01 NS091075 · United States
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