ADP-ribosylation of the inhibitory guanine nucleotide regulatory protein (Ni) as a possible mechanism underlying development of beta-adrenergic responses during primary culture of rat hepatocytes.

Adenosine Diphosphate Ribose/metabolism Adenylyl Cyclases/metabolism Animals Bacterial Toxins/pharmacology Cell Membrane/metabolism Cells, Cultured GTP-Binding Proteins/metabolism Liver/metabolism Macromolecular Substances Nucleoside Diphosphate Sugars/metabolism Pertussis Toxin Rats Receptors, Adrenergic, alpha/metabolism Receptors, Adrenergic, beta/metabolism Time Factors Virulence Factors, Bordetella

Bacterial Toxins Macromolecular Substances Nucleoside Diphosphate Sugars Receptors, Adrenergic, alpha Receptors, Adrenergic, beta Virulence Factors, Bordetella Adenosine Diphosphate Ribose Pertussis Toxin GTP-Binding Proteins Adenylyl Cyclases