[Introduction of DNA sequences of Rous sarcoma virus into Drosophila and mouse genomes by microinjections into ova].

Vvedenie posledovatel'nosteĭ DNK virusa sarkomy Rausa v genomy drosofily i myshi putem mikroin''ektsiĭ v iaĭtsekletki.

Molekuliarnaia biologiia ·Vol. 19 ·No. 3 ·1985-00-00 ·Pages 760-6

Gazarian KG, Gol'tsov VA, Nabirochkin SD, Eshkind LG, Tarantul VZ

Abstract

The paper covers experimental results of introducing exogenic genetic material, namely DNA sequences of the Rous sarcoma virus, by microinjections in mice zygotes and Drosophila early embryos. In a number of cases integration of viral DNA into genomes of these organisms was detected. Blot-hybridizations analysis of cell DNA proved that the inserted viral sequences undergo rearrangements in the course of integration.

MeSH Terms

Animals Avian Sarcoma Viruses/genetics Cloning, Molecular DNA/genetics DNA, Viral/genetics Drosophila melanogaster/genetics Female Male Mice Mice, Inbred C57BL Microinjections Nucleic Acid Hybridization Plasmids Transfection Zygote/microbiology

Chemicals

DNA, Viral DNA

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Gazarian K G

Gol'tsov V A

Nabirochkin S D

Eshkind L G

Tarantul V Z

Article Info

Journal

Molekuliarnaia biologiia

Abbr.

Mol Biol (Mosk)

ISSN

0026-8984

Published

1985-00-00

Pages

760-6

Language

rus

Region

Russia (Federation)

NLM ID

0105454

Subset

External Links

PubMed source

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[Introduction of DNA sequences of Rous sarcoma virus into Drosophila and mouse genomes by microinjections into ova].

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