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PMID: 2995112 Published · ppublish English Journal Article Review

Autophagy and lysosomal proteolysis in the liver.

Experientia ·Vol. 41 ·No. 9 ·1985-09-15 ·Pages 1089-95

Grinde B

Abstract

Autophagy is defined as any process whereby cellular macromolecules destined for degradation gain access to the lysosomes. A review is presented on the physiological significance, mechanisms and regulation of autophagy in hepatocytes, concentrating on the issue of regulation. The article ends by discussing techniques available for future research.

MeSH Terms
Amino Acids/metabolism Animals Asparagine/metabolism Calcium/metabolism Cyclic AMP/metabolism Epinephrine/physiology Glucagon/physiology Glucocorticoids/physiology Glutamine/metabolism Hydrogen-Ion Concentration Hydrolases/metabolism Insulin/physiology Intermediate Filaments/physiology Kynurenine/metabolism Liver/cytology Lysosomes/physiology Membranes/physiology Models, Biological Peptide Hydrolases/metabolism Phagocytosis Thyroxine/physiology
Chemicals
Amino Acids Glucocorticoids Insulin Glutamine Kynurenine Asparagine Glucagon Cyclic AMP Hydrolases Peptide Hydrolases Thyroxine Calcium Epinephrine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Grinde B
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Article Info
Journal
Experientia
Abbr.
Experientia
ISSN
0014-4754
DOI
10.1007/BF01951685
Published
1985-09-15
Pages
1089-95
Language
English
Region
Switzerland
NLM ID
0376547
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01951685
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