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PMID: 30016409 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

Reproducible and replicable comparisons using SummarizedBenchmark.

Bioinformatics (Oxford, England) ·Vol. 35 ·No. 1 ·2019-00-01 ·Pages 137-139

Kimes PK, Reyes A

Abstract

Benchmark studies are widely used to compare and evaluate tools developed for answering various biological questions. Despite the popularity of these comparisons, the implementation is often ad hoc, with little consistency across studies. To address this problem, we developed SummarizedBenchmark, an R package and framework for organizing and structuring benchmark comparisons. SummarizedBenchmark defines a general grammar for benchmarking and allows for easier setup and execution of benchmark comparisons, while improving the reproducibility and replicability of such comparisons. We demonstrate the wide applicability of our framework using four examples from different applications. SummarizedBenchmark is an R package available through Bioconductor (http://bioconductor.org/packages/SummarizedBenchmark). Supplementary data are available at Bioinformatics online.

MeSH Terms
Computational Biology/methods Reproducibility of Results Software
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kimes Patrick K
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA. | Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Reyes Alejandro
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA. | Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
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Article Info
Journal
Bioinformatics (Oxford, England)
Abbr.
Bioinformatics
ISSN
1367-4811
Published
2019-00-01
Pages
137-139
Language
English
Region
England
NLM ID
9808944
PMCID
PMC6298041
Subset
IM
Grants
NHGRI NIH HHS · P41 HG004059 · United States
NIGMS NIH HHS · R01 GM083084 · United States
NHGRI NIH HHS · R01 HG005220 · United States
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