Cisplatin neuropathy with Lhermitte's sign.

Journal of neurology, neurosurgery, and psychiatry ·Vol. 49 ·No. 1 ·1986-01-00 ·Pages 96-9

Dewar J, Lunt H, Abernethy DA, Dady P, Haas LF

Abstract

Following chemotherapy with cis-diamminedichloroplatinum II (cisplatin) three patients developed Lhermitte's sign and peripheral neuropathy. The toxic side effects did not become apparent until after treatment had ceased. Because of increasing use of cisplatin to achieve lasting remission in patients with malignant disease proprioceptive and myelopathic side effects may become increasingly common.

MeSH Terms

Adult Cisplatin/adverse effects Female Humans Male Middle Aged Peripheral Nervous System Diseases/chemically induced Proprioception Spinal Cord Diseases/chemically induced

Chemicals

Cisplatin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Dewar J

Lunt H

Abernethy D A

Dady P

Haas L F

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15 references, click to expand

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Article Info

Journal

Journal of neurology, neurosurgery, and psychiatry

Abbr.

J Neurol Neurosurg Psychiatry

ISSN

0022-3050

DOI

10.1136/jnnp.49.1.96

Published

1986-01-00

Pages

96-9

Language

English

Region

England

NLM ID

2985191R

PMCID

PMC1028656

Subset

External Links

PubMed source DOI: 10.1136/jnnp.49.1.96 PMC Full Text View journal details

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