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PMID: 3013568 Published · ppublish English Clinical Trial Comparative Study Journal Article Randomized Controlled Trial

Sulbactam/ampicillin versus cefoxitin in the treatment of obstetric and gynaecological infections.

Drugs ·Vol. 31 Suppl 2 ·1986-00-00 ·Pages 18-21

Senft HH, Stiglmayer R, Eibach HW, Koerner H

Abstract

Preliminary results of a randomised trial comparing parenteral sulbactam 1g plus ampicillin 2g every 8 hours and cefoxitin 2g every 8 hours in 75 patients with gynaecological infection are reported. Clinical and bacteriological cure were achieved in 87% and 91% of patients treated with sulbactam/ampicillin compared with 83% and 59% treated with cefoxitin. Both treatments were well tolerated.

MeSH Terms

Adolescent Adult Ampicillin/administration & dosage,therapeutic use Bacterial Infections/drug therapy Cefoxitin/therapeutic use Child Clinical Trials as Topic Drug Therapy, Combination Endometritis/drug therapy Female Genital Diseases, Female/drug therapy Humans Penicillanic Acid/administration & dosage,therapeutic use Peritonitis/drug therapy Random Allocation Salpingitis/drug therapy Sulbactam beta-Lactamase Inhibitors

Chemicals

beta-Lactamase Inhibitors Cefoxitin Ampicillin Penicillanic Acid Sulbactam

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Senft H H

Stiglmayer R

Eibach H W

Koerner H

Article Info

Journal

Drugs

Abbr.

Drugs

ISSN

0012-6667

DOI

10.2165/00003495-198600312-00005

Published

1986-00-00

Pages

18-21

Language

English

Region

New Zealand

NLM ID

7600076

Subset

External Links

PubMed source DOI: 10.2165/00003495-198600312-00005 View journal details

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Sulbactam/ampicillin versus cefoxitin in the treatment of obstetric and gynaecological infections.

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