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PMID: 3014686 Published · ppublish English Comparative Study Journal Article

Assays of sulbactam in the presence of ampicillin.

Therapeutic drug monitoring ·Vol. 8 ·No. 2 ·1986-00-00 ·Pages 223-7

Foulds G, Gans DJ, Girard D, Whall TJ

Abstract

Three assays for sulbactam, a beta-lactamase inhibitor, in serum in the presence of ampicillin were compared. A synergistic bioassay, a gas chromatographic assay with detection by mass spectrometry, and a high performance liquid chromatography assay were similar with respect to both accuracy and precision.

MeSH Terms
Ampicillin/blood,pharmacology Biological Assay Chemical Phenomena Chemistry Chromatography, High Pressure Liquid Drug Synergism Gas Chromatography-Mass Spectrometry Humans Penicillanic Acid/blood Sulbactam beta-Lactamase Inhibitors
Chemicals
beta-Lactamase Inhibitors Ampicillin Penicillanic Acid Sulbactam
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Foulds G
Gans D J
Girard D
Whall T J
Article Info
Journal
Therapeutic drug monitoring
Abbr.
Ther Drug Monit
ISSN
0163-4356
DOI
10.1097/00007691-198606000-00018
Published
1986-00-00
Pages
223-7
Language
English
Region
United States
NLM ID
7909660
Subset
IM
External Links
PubMed source DOI: 10.1097/00007691-198606000-00018 View journal details
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