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PMID: 3018296 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Reovirus guanylyltransferase is L2 gene product lambda 2.

Journal of virology ·Vol. 60 ·No. 1 ·1986-10-00 ·Pages 307-11

Cleveland DR, Zarbl H, Millward S

Abstract

Reovirus guanylyltransferase, studied as a covalent enzyme-GMP intermediate, was used to guanylate appropriate acceptor molecules in vitro to produce authentic cap structures. Guanylyltransferase activity was associated with lambda 2, the 140-kilodalton product of the L2 gene segment of reovirus serotypes 1 and 3.

MeSH Terms
Genes Genes, Viral Mammalian orthoreovirus 3/enzymology Nucleotidyltransferases/genetics RNA Caps RNA, Double-Stranded/genetics RNA, Viral/genetics Reoviridae/enzymology Viral Proteins/genetics
Chemicals
RNA Caps RNA, Double-Stranded RNA, Viral Viral Proteins Nucleotidyltransferases guanylyltransferase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cleveland D R
Zarbl H
Millward S
References (34)
34 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.60.1.307-311.1986
Published
1986-10-00
Pages
307-11
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC253932
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.60.1.307-311.1986 PMC Full Text View journal details
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