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PMID: 302126 Published · ppublish English Journal Article

In vitro synthesis of alpha-1-antitrypsin in long term monolayer human liver cell cultures.

Biomedicine / [publiee pour l'A.A.I.C.I.G.] ·Vol. 27 ·No. 3 ·1977-04-00 ·Pages 116-9

Gautier M, Martin JP, Polini G

Abstract

Explants for long term monolayer liver cell cultures were taken from individuals having PiM or PiZ phenotypes. Radioactive labelling, using I125 and an original method, permitted the quantitative measurement of AAT in vitro and more important, allowed Pi phenotype determination.

MeSH Terms
Cells, Cultured Child Humans Liver/metabolism,pathology Liver Cirrhosis/pathology Phenotype alpha 1-Antitrypsin/biosynthesis
Chemicals
alpha 1-Antitrypsin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gautier M
Martin J P
Polini G
Article Info
Journal
Biomedicine / [publiee pour l'A.A.I.C.I.G.]
Abbr.
Biomedicine
ISSN
0300-0893
Published
1977-04-00
Pages
116-9
Language
English
Region
France
NLM ID
0361342
Subset
IM
External Links
PubMed source
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