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PMID: 302314 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Antigens expressed by human B lymphocytes and myeloid stem cells.

The Journal of experimental medicine ·Vol. 146 ·No. 4 ·1977-10-01 ·Pages 1143-5

Cline MJ, Billing R

Abstract

Antisera prepared against papain-digested spleen cell membranes were known to by cytotoxic for normal and neoplastic human B lymphocytes and for a majority of acute and chronic myeloid leukemic cells. It is now shown that these antisera are also cytotoxic for normal myeloid stem cells (CFU-C), thus providing a probable explanation for their occurrence in myeloid neoplasia.

MeSH Terms
B-Lymphocytes/immunology Granulocytes/immunology Hematopoietic Stem Cells/immunology Humans Macrophages/immunology Spleen/immunology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Cline M J
Billing R
References (9)
9 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.146.4.1143
Published
1977-10-01
Pages
1143-5
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2180819
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.146.4.1143 PMC Full Text View journal details
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