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PMID: 30275051 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Comment

Sexual Inequality in the Cancer Cell.

Cancer research ·Vol. 78 ·No. 19 ·2018-00-01 ·Pages 5504-5505

Arnold AP, Disteche CM

Abstract

Investigating sex differences in cancer will improve therapy for both sexes and discover sex-specific protective mechanisms. Two recent analyses by Lopes-Ramos and colleagues and Li and colleagues point to specific gene regulatory networks and genomic alterations associated with sex differences in tumor incidence and progression. Integrating this information with emerging concepts about sex biases in the genome may help focus attention on factors that shift the odds for tumor growth. Cancer Res; 78(19); 5504-5. ©2018 AACR See related articles by Li et al., p. 5527, and Lopes-Ramos et al., p. 5538.

MeSH Terms
Biomarkers Female Humans Male Neoplasms/genetics Oncogenes Sex Characteristics Socioeconomic Factors
Chemicals
Biomarkers
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Arnold Arthur P
Department of Integrative Biology & Physiology, and Laboratory of Neuroendocrinology of the Brain Research Institute, UCLA, Los Angeles, California. [email protected].
Disteche Christine M
Departments of Pathology and Medicine, University of Washington, Seattle, Washington.
References (10)
10 references, click to expand
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Article Info
Journal
Cancer research
Abbr.
Cancer Res
ISSN
1538-7445
DOI
10.1158/0008-5472.CAN-18-2219
Email
[email protected]
Published
2018-00-01
Pages
5504-5505
Language
English
Region
United States
NLM ID
2984705R
PMCID
PMC6204258
Subset
IM
Grants
NICHD NIH HHS · R01 HD076125 · United States
NICHD NIH HHS · R21 HD090637 · United States
NIGMS NIH HHS · R01 GM113943 · United States
NIGMS NIH HHS · R01 GM046883 · United States
NHLBI NIH HHS · R01 HL131182 · United States
Corrections
CommentOn
PMID: 30275052
CommentOn
PMID: 30275053
External Links
PubMed source DOI: 10.1158/0008-5472.CAN-18-2219 PMC Full Text View journal details
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