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PMID: 3028647 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Deletion analysis of GAL4 defines two transcriptional activating segments.

Cell ·Vol. 48 ·No. 5 ·1987-03-13 ·Pages 847-53

Ma J, Ptashne M

Abstract

We describe the activities of a wide array of deletion mutants of GAL4, a yeast transcriptional activator. We identify two short regions of GAL4, each of which activates transcription when fused to the DNA-binding region of the molecule. Very large portions of GAL4 are not required for gene activation.

MeSH Terms
Base Sequence Chromosome Deletion DNA Restriction Enzymes Galactose/metabolism Mutation Plasmids Saccharomyces cerevisiae/genetics Transcription, Genetic
Chemicals
DNA Restriction Enzymes Galactose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ma J
Ptashne M
Article Info
Journal
Cell
Abbr.
Cell
ISSN
0092-8674
DOI
10.1016/0092-8674(87)90081-x
Published
1987-03-13
Pages
847-53
Language
English
Region
United States
NLM ID
0413066
Subset
IM
Grants
NIGMS NIH HHS · GM32308 · United States
External Links
PubMed source DOI: 10.1016/0092-8674(87)90081-x View journal details
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